Grapefruit and grapefruit juice might connect with sildenafil and result in unwanted side effects. Stay away from the use of grapefruit solutions even though taking sildenafil.
Sildenafil shouldn't be taken by people who acquire nitrates including nitroglycerin (glycerin trinitrate), as this could cause a severe and most likely fatal fall in blood pressure.[three]
In The us, Pfizer gained two patents for sildenafil: one for its sign to take care of heart problems (marketed as Revatio) and One more for its indicator to treat erectile dysfunction (marketed as Viagra). The material is identical under the two trade names.[seventy five]
It can be crucial to keep all medication outside of sight and attain of youngsters as numerous containers (for instance weekly pill minders and people for eye drops, creams, patches, and inhalers) are not youngster-resistant and youthful youngsters can open up them effortlessly.
The key sign of sildenafil is treatment method of erectile dysfunction (incapability to sustain a satisfactory erection to complete intercourse).
an erection that won't go away (priapism). In case you have an erection that lasts more than four several hours, get health-related assistance straight away.
Acetildenafil and other artificial structural analogs of sildenafil that are PDE5 inhibitors are identified as adulterants in many "herbal" aphrodisiac merchandise sold in PDE-5.com excess of-the-counter. These analogs have not gone through any of the demanding testing that medications like sildenafil have passed, and therefore have unknown aspect-outcome profiles.
Should you be a girl and also you are getting sildenafil to take care of PAH, inform your health practitioner if you are pregnant, prepare to be pregnant, or are breastfeeding. Should you develop into pregnant whilst getting sildenafil, connect with your physician.
-This drug is indicated for therapy of erectile dysfunction in male Grownup individuals, and is usually marketed as Revatio (R) to take care of PAH in young children and adults.
don't take Avenue medications containing nitrates such as amyl nitrate and butyl nitrate ('poppers') though getting sildenafil.
Sildenafil may result in Uncomfortable side effects. Tell your physician if any of those signs or symptoms are severe or don't go away:
 Scientific studies on the effects of viagra when utilized recreationally are limited, but suggest it's got very little influence when utilized by Individuals not suffering from erectile dysfunction. In one analyze, a twenty five-mg dose was demonstrated to result in no substantial alter in erectile quality, but did lessen the postejaculatory refractory time. This review also famous a substantial placebo effect in the Command team.
convey to all of your healthcare providers that you'll be getting sildenafil. In the event you ever will need unexpected emergency healthcare treatment for your heart problem, the Health care companies who treat you must know if you final took sildenafil.
Those using protease inhibitors are suggested to limit their utilization of sildenafil to no more than one 25 mg dose every single forty eight hrs.[two] Other medicine that interfere While using the metabolism of sildenafil involve erythromycin and cimetidine, both of which may also result in prolonged plasma half-lifestyle amounts.